Meet the crew
 We are scientists (both youngsters and old but young-at-heart) with diverse backgrounds and affiliations that bring wide-ranging perspectives and experience to our laboratory, university, and community. We are a fun, creative team that does not shy away from hard work required in pursuing our science. Our collective training is in the biological sciences, omics technologies, computing, and veterinary medicine. Members of our lab are routinely tasked to help train next-generation veterinarian-scientists in our college through intensive lab rotations and coaching. We strive to make paradigm-shifting discoveries and advance a new generation of scientific leaders.

Kang-Hoon Lee

Research professor
 As an appointed research professor, I help manage overall research activity in the lab and oversee trainees and their productivity. My research interests mainly revolves around the roles that long non-coding RNAs play in cancer and immunity.
PhD, Microbiology, Chungnam National University (Daejeon, KR)
B.Sc/M.Sc., Microbial Genetics, Chungnam National University (Daejeon, KR)
2011-2012 Independent researcher, Department of Surgery, UC Davis
2012-2015 Independent researcher, Shriners Hospitals for Children
2012-2015 Assistant project scientist, California State University, Sacramento
Somatic Mutation of PIK3CA (H1047R) Is a Common Driver Mutation Hotspot in Canine Mammary Tumors as Well as Human Breast Cancers.
Lee KH et al. Cancers (Basel). 2019
Methylation of LINE-1 in cell-free DNA serves as a liquid biopsy biomarker for human breast cancers and dog mammary tumors.
Lee KH et al. Scientific Reports. 2019
Transcriptome Signatures of Canine Mammary Gland Tumors and Its Comparison to Human Breast Cancers.
Lee KH et al. Cancers (Basel). 2018
Click: NCBI List

Dabin Lee

Post-doctoral fellow
 I am interested in the biology of obesity. I am currently working on uncovering the potential thermogenic role of a gene target I identified in mouse white adipose tissues. I have experience in proteomics and mice experiments and would love to further my scientific skillset. I love music, playing musical instruments, and also participating in volunteering activities. I plan on shifting scientific fields when I do my post-doc. 
M.Sc., Veterinary Biomedical Sciences, Seoul National University (Seoul, KR)
B.Sc.,  Biotechnology, Pukyong National University (Busan, KR)
CXCL5 secreted from macrophages during cold exposure mediates white adipose tissue browning
Lee D et al. Journal of Lipid Research. 2021
CCL4 enhances preosteoclast migration and its receptor CCR5 downregulation by RANKL promotes osteoclastogenesis.
Lee D et al. Cell Death & Disease. 2018
Click: NCBI List

Tae-Jin Shin

PHD STUDENT
 I am exploring how long non-coding RNAs can act as critical regulators of epigenetic modification. In general, the idea of epigenetic inheritance intrigues me. I believe success is confounded by daily habitual routines!  
B.Sc., Animal Bio Science, Konkuk University (Seoul, KR) 
Concise approach for screening long non-coding RNAs functionally linked to human breast cancer associated genes.
Shin TJ et al. Experimental & Molecular Pathology. 2019
Click: NCBI List

Najeong Kim

PHD STUDENT
 I am a wanderer in the mysterious world of non-coding RNA. My current research is focused on discovering a key long non-coding RNA factor that plays an important role in cardiac function using mouse as a model system. I look at myself as a persistent trainee who hopes to become a great scientist in the (near) future! I love doing pilates and yoga.
B.Sc., Biological Sciences, Sookmyung Women's University (Seoul, KR)
Spatiotemporal expression of long noncoding RNA Moshe modulates heart cell lineage commitment.
Na-Jung Kim et al. RNA Biology. 2021

A-Reum Nam

PHD STUDENT
 I am studying the epigenetic landscapes of immunity in both human and canine cancers. I find it interesting that certain biological phenomena can be controlled by specific mechanistic logic. In my research, I use a whole lot of bioinformatics to reveal, in a hypothesis-free manner, the many secrets of cancer. I enjoy sports (i.e., ski, swimming, bowling) and taking Vlogs and making photographic memories. My goal is to publish my research in the journal Nature Medicine, which has an impact factor of 36.13. 
B.Sc./M.Sc., Biomedical Laboratory Science, Konyang University (Daejeon, KR)
Alternative methylation of intron motifs is associated with cancer-related gene expression in both canine mammary tumor and human breast cancer.
Nam AR et al. Clinical Epigenetics. 2020
Click: NCBI List

HuiSu Kim

PHD STUDENT
 I am fascinated by the biogenesis and function of exosomes. I look at exosomes as "molecular mails" that are released by cells and package some important raw and functional biological materials and thus bridge important connections between cells and the microenvironment. The focus of my research is to piece together the intricate puzzle that encompasses the regulation of generation and function of these lipid vesicles and the materials that they carry during tumor progression.
B.Sc., Biochemistry, Chungbuk National University (Cheongju, KR)
Click: NCBI List

Mark Borris Aldonza

PHD STUDENT
 I identify as a cancer biologist who works at the intersection of chemical biology, immunity, and glycobiology. I aim to discover new mechanisms of metastasis, immune evasion, and tumor evolution using chemical and genetic tools, bioinformatics, animal models, and patient-derived organoids. I also have an interest in exploring the RNA world in the context of cancer. Outside the lab, I have a fond interest in astronomy, learning foreign cultures, and politics. I am not a K-pop fan but I love dancing to the tunes of Nunu Nana (Jessie), God's Menu (Stray Kids), or Not Shy (Itzy). I enjoy experimenting with food and secretly hopes to become an expert in molecular gastronomy. I play tennis and recently learned how to swim. My goal is to run my own (well-funded) lab focused on disease evolution and train the next-generation science X-Men (or Avengers).
 B.Sc., Biological Sciences, Science & Technology Policy, KAIST (Daejeon, KR)
2012-2013 Research technician, College of Pharmacy, Seoul National University
2013-2015 Research assistant, College of Veterinary Medicine, Seoul National University
2017 Visiting research fellow, Institute of Molecular Biotechnology (IMBA) of AAS
2016-2020 Research assistant, Department of Chemical & Biomolecular Engineering, KAIST
Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms.
Aldonza MBD et al. Science Advances. 2020
Paraoxonase-1 (PON1) induces metastatic potential and apoptosis escape via its antioxidative function in lung cancer cells.
Aldonza MBD et al. Oncotarget. 2017
Paclitaxel-resistant cancer cell-derived secretomes elicit ABCB1-associated docetaxel cross-resistance and escape from apoptosis through FOXO3a-driven glycolytic regulation.
Aldonza MB et al. Experimenal & Molecular Medicine. 2017
Click: NCBI List

Hyeon-Ji Hwang

PHD STUDENT
 I am interested on how cholesterol is dynamically regulated and contributes to carcinogenesis. My goal is to identify a new key regulator in cholesterol metabolism and how manipulating this "control factor" can reshape tumor progression and the way tumor interact with its microenvironment. Science is a big world and so I want to further my studies and training to eventually find my own niche! In my free time, I am a pâtissier! I enjoy baking desserts for my lab mates!  
B.Sc., Chemical Engineering & Biotechnology, Korea Polytechnic University (Siheung, KR)
Somatic Mutation of PIK3CA (H1047R) Is a Common Driver Mutation Hotspot in Canine Mammary Tumors as Well as Human Breast Cancers.
Lee KH, Hwang HJ et al. Cancers (Basel). 2019
Click: NCBI List

Keunhong Son

PHD STUDENT
 I am a bioinformatician who strives to learn how we can use and develop computational models and methods to understand and control complex biological systems and treat disease. I look at cancer as a systems-level disease and therefore believe that a global view of the multiple levels of dysfunction in cancer will best inform clinical management strategies. I am training to become adept at using machine learning methods to leverage my research. Other than science, I love skydiving, scuba diving, and snowboarding! 
B.Sc./M.Sc., Microbiology, Dankook University (Cheonan, KR)
Nucleoporin 210 serves a key scaffold for SMARCB1 in liver cancer.
Hong SH, Son K et al., Cancer Research. 2020
A Simple Guideline to Assess the Characteristics of RNA-Seq Data.
Son K et al., BioMed Research International. 2018
Click: NCBI List

Jeong-Woon Lee

PHD STUDENT
 As a veterinarian, I work on science that benefits both humans and animals. I am interested in dissecting the chromatin accessibility profiles of human and canine cancers with the hopes to provide clinical implications that would aid in managing cancer in a cross-species manner. I am working to become an expert in using ATAC-seq and other omics tools in addressing important medical problems. I like gaming, exploring new places, and playing with my dog, Choco! 
DVM, Veterinary Medicine, Seoul National University (Seoul, KR)

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Hoonyoung Yoon

PHD STUDENT
 I am an outgoing adventurist! I love exploring the many ways science can positively impact humanity. I am currently involved in several projects but hoping to become an expert bioinformatician. My goal is to develop tools that would help other scientists answer their deep questions about diseases. Life is not what it is without travelling!  
 B.Sc., Biomedical Laboratory Science, Yonsei University (Wonju, KR)
2019-2020 Research intern, KIST

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Min-Hong Cho

PHD STUDENT
 Mankind had achieved a lot of great things over the past few decades. But still failed in conquering cancer. Because of this, cancer is a subject that has many challenges ahead. Personally, I love challenges, and use of my creativity in solving them. As a future scientist, my goal is to use my strength as a veterinarian to find and link significant features between animals and humans that could lead us to the future. I don’t know how much I will achieve, but I have my fingers crossed.
DVM, Veterinary Medicine, Konkuk University (Seoul, KR)

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Heung-Seok Bae

PHD STUDENT
 I have always been interested on what goes awry when cancer develops. I believe that the solution to "curing" cancer lies in our ability to understand the complexity of human and animal biology. I enjoy learning new experimental techniques and new kind of science. My research focuses on how a specific transcription factor could be leveraged in treatment of lung cancer.
M.Sc., Natural Products Science, Seoul National University (Seoul, KR)
B.Sc., Plant Resource Development, Sunchon National University (Suncheon, KR)

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A-In Kim

Lab Intern
 As I've spent student-years in the US, I'm enjoying my new journey here in Korea at SNU! My research topic would be determined a while later, but I look forward to conducting innovative experiments related to canine and human health. My long-term goal is to launch my own company after getting a Ph.D degree. (p.s. I love horse-back riding, dancing, and snuggling up with my dogs!)
B.Sc., Animal Science, UC Davis (California, USA)

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Su-Jin Jeong

PhD student, on-leave
 My research interest lies in understanding epigenetic regulatory mechanisms of canine and human cancer progression. Eventually, I hope my research leads to the development of clinically important disease biomarkers. I like hanging out with friends, taking photos, and travelling!  
B.Sc., Microbiology, Chungbuk National University (Cheongju, KR)
Genome-Wide Methylation Profiling in Canine Mammary Tumor Reveals miRNA Candidates Associated with Human Breast Cancer
Jeong et al. Cancers (Basel). 2019
Click: NCBI List

Sang-Hyuk Yoon

PhD student, on-military leave
 I plan to become an expert in proteogenomics. My long-term goal is to contribute to the understanding of complex relationship between genotype, pathology, and disease phenotypes. Outside the lab, I enjoy cycling and hiking.
B.Sc., Molecular & Cellular Biology, Dong-A University (Busan, KR)
2020-present Researcher (military duty), Protanbio Inc.

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